WorkBeads™ 40 TREN resin for multimodal Ion Exchange Chromatography (IEX) has a ligand that is positively charged below approx. pH 9. The resin can be used for several different applications, in particular due to its higher salt tolerant properties, e.g. for multimodal IEX, for sample clean-up in monoclonal antibody (mAb) purification processes in order to guard the Protein A column from chromatins and other host cell impurities, or as a polishing step in the mAb purification process.
- Differential selectivity due to higher salt tolerance and multimodal properties
- Reduced fouling of Protein A resins by chromatin and host cell impurity removal
- High binding capacity and purity